
Publications
- Jonker MJ, Bruning O, van Iterson M, Schaap MM, van der Hoeven TV, Vrieling H, Beems RB, de Vries A, van Steeg H, Breit TM, Luijten M. Finding transcriptomics biomarkers for in vivo identification 1 of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models. Carcinogenesis 2009 accepted
- Oomes SJCM, Jonkers M, Wittink F, Hehenkamp JO, Breit TM, Brul S. The effect of calcium on the transcriptome of sporulating B. subtilis cells. Int J Food Microbiol. 2009 Aug 15;133(3):234-242
- Hackenberg C, Engelhardt E, Matthijs HCP, Wittink F, Bauwe H, Kaplan A, Hagemann M Photorespiratory 2-phosphoglycolate metabolism and photoreduction of O2 cooperate in high light acclimation of Synechocystis sp. strain PCC 6803 Planta accepted.
- Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LH, van der Horst GT, Brüning JC, Niessen CM, Hoeijmakers JH, Schumacher B. Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity. Nat Cell Biol. 2009 May;11(5):604-615
- van Hooff SR, Koster J, Hulsen T, van Schaik BDC, Roos M, van Batenburg MF, Versteeg R, van Kampen AHC.The construction of genome-based transcriptional units. OMICS, 2009 Apr;13(2):105-114
- Schumacher B, van der Pluijm I, Moorhouse MJ, Kosteas T, Robinson AR, Suh Y, Breit TM, van Steeg H, Niedernhofer LJ, van IJcken W, Bartke A, Spindler SR, Hoeijmakers JH, van der Horst GT, Garinis GA. Delayed and accelerated aging share common longevity assurance mechanisms. PLoS Genet. 2008 Aug 15;4(8):e1000161
- Luppens SB, Kara D, de Jong, Jonker MJ, Hoefsloot H, Wittink F, Bandounas L, Breit TM, ten Cate JM, Crielaard W. Harmless bacterium can evoke increased antimicrobial resistance in human pathogen grown in biofilm. Oral Microbiol Immunol. 2008 Jun;23(3):183-189
- Owen J, Hedley BA, Svendsen C, Wren J, Jonker MJ, Hankard PK, Lister LJ, Stürzenbaum SR, Morgan AJ, Spurgeon DJ, Blaxter ML, Kille P. Transcriptome profiling of developmental and xenobiotic responses in a keystone soil animal, the oligochaete annelid Lumbricus rubellus. BMC Genomics 2008 Jun 3;9:266
- Svendsen C, Owen J , Kille P, Wren J, Jonker MJ, Headley BA , Morgan AJ, Blaxter ML, Stürzenbaum SR, Hankard PK, Lister LJ, Spurgeon DJ. Comparative Transcriptomic Responses to Chronic Cadmium, Fluoranthene, and Atrazine Exposure in Lumbricus rubellus. Environ. Sci. Technol. 2008 Jun 1;42(11):4208-4214
- Vroling AB, Jonker MJ, Breit TM, Fokkens WJ, van Drunen CM. Comparison of expression profiles induced by dust mite in airway epithelia reveals a common pathway. Allergy 2008 Apr;63(4):461-467
- Bruning O, Bruins W, Jonker MJ, Zwart E, van der Hoeven T, Pennings JLA, Rauwerda H, de Vries A, Breit TM. Absence of Ser389 phosphorylation in p53 affects the basal gene-expression level of many p53-dependent genes and alters the biphasic response to UV exposure in MEFs. Mol Cell Biol. 2008 Mar;28(6):1974-1987
- Smit van Dixhoorn MGA, Munir R, Stad R, de Haan M, van der Hoeven T, Rauwerda H, Breit TM, Thallinger GG, Wadee AA. Gene Expression Profiling Of Suppressor Mechanisms In Tuberculosis. Mol Immunol. 2008 Mar;45(6):1573-1586
- Vroling AB, Jonker MJ, Luiten S, Breit TM, Fokkens WJ, van Drunen CM. Comparison of gene expression in response to house dust mite allergen by epithelial cells of allergic and healthy individuals, separately and combined. Am J Respir Cell Mol Biol. 2008 Mar;38(3):293-299
- Mirabella R, Rauwerda H, Struys EA, Haring MA, Schuurink R. Mapping of the her1 mutant in Arabidopsis thalania. Plant J. 2008 Jan;53(2):197-213
- Aronica E, Boer K, Becker A, Redeker S, Spliet WGM, van Rijen PC, Wittink F, Breit TM, Wadman WJ, Gorter JA. Gene expression profile analysis of epilepsy-associated gangliogliomas. Neuroscience 2008 Jan 2;151(1):272-292
- Baken KA, Pennings JLA, Jonker MJ, Schaap MM, de Vries A, van Steeg H, Breit TM, van Loveren H. Identification of overlap in gene expression profiles induced by model compounds offers opportunities for immunotoxicity screening. Toxicology and Applied Pharmacology 2008 Jan 1;226(1):46-59
- Banus S, Vandebriel RJ, Pennings JLA, Gremmer ER, Wester PW, van Kranen HJ, Breit TM, Demant P, Mooi FR, Hoebee B, Kimman TG. Bordetella pertussis susceptibility genes described by comparison of gene expression profiles of two strains of mice. BMC microbiology 2007 Oct 12;7:88
- Bruins W, Jonker MJ, Bruning O, Pennings J, Schaap M, Hoogervorst E, Speksnijder E, van Steeg H, Breit TM, de Vries A. Delayed expression of Apoptotic and Cell Cycle processes in Carcinogen-Exposed Bladders of Mice lacking p53.S389A Phosphorylation. Carcinogenesis 2007 Aug;28(8):1814-1823
- Banus HA, Pennings JLA, Vandebriel RJ, Wester PW, Breit TM, Mooi FR, Hoebee B, Kimman TG. Lung response to Bordetella pertussis infection in mice identified by gene-expression profiling. Immunogenetics 2007, Jul;59(7):555-564
- Keijser BJF, ter Beek A, Rauwerda H, Schuren F, Montijn R, van der Spek H, Brul S. Analysis of temporal gene expression during Bacillus subtilis spore germination and outgrowth. J. Bacteriol. 2007, May;189(9):3624-3634
- Gorter JA, van Vliet EA, Rauwerda H, Breit TM, Stad R, van Schaik L, Vreugdenhil E, Redeker S, Hendriksen E, Aronica E, Lopes da Silva FH, Wadman WJ. Dynamic changes of proteases and protease inhibitors revealed by microarray analysis in CA3 and entorhinal cortex during epileptogenesis in the rat Journal: Epilepsia 2007 48 Suppl 5:53-64
- Kooter IM, Pennings J, Fokkens P, Leseman D, Boere J, Gerlofs M, Cassee F, Schalk JA, Orzechowski T, Schaap M, Breit TM, Dormans J, van Oostrom C, de Vries A, van Steeg H. Ozone induces clear cellular and molecular responses in the mouse lung independently of the transcription-coupled repair status. J Appl Physiol. 2007, Mar;102(3):1185-92
- Baken KA, Pennings JLA, Breit TM, de Vries A, van Steeg H, van Loveren H, Gene expression profiling of bis(tri-n-butyltin)oxide (TBTO) induced immunotoxicity in mice and rats. Journal of Immunotoxicology 2006 Dec 1;3(4):227-244
- Gorter JA, van Vliet EA, Aronica E, Breit TM, Rauwerda H, Lopes da Silva FH, Wadman WJ. Potential new anti-epileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy. J Neurosci. 2006, Oct 25;26(43):11083-11110
- Yang XX, Breit TM, Verschure PJ. Dysregulation of gene expression in Huntington's disease by epigenetic changes in chromatin structure. Journal of Neurology Neurosurgery and Psychiatry 2005 Oct;76: Suppl. 4 Abstract
- Versteeg R, van Schaik BD, van Batenburg MF, Roos M, Monajemi R, Caron H, Bussemaker HJ, van Kampen AH. The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes. Genome Res. 2003, Sep;13(9):1998-2004